Background. Next Generation Sequencing (NGS) has dramatically enhanced our ability to sequence genomes, but not to assemble them. In practice, many published genome sequences remain in the state of a large set of contigs. Each contig describes the …
Given a finite set of strings, the Median String problem consists in finding a string that minimizes the sum of the edit distances to the strings in the set. Approximations of the median string are used in a very broad range of applications where one …